It comes hours ahead of planned Friday protests against Mr Assad's regime.
Overnight, at least five people were killed during raids by security forces, activists say.
The deaths occurred in the north-eastern city of Deir al-Zour and a suburb of the capital Damascus, in the south-west of the country.
The demonstrations, which started in mid-March, have been met by a fierce crackdown that has killed more than 1,500 civilians and seen 26,000 people arrested.
More than 12,600 are still in detention, the Avaaz rights group says, and 3,000 others are missing, with family members unable to establish if they are still alive.
Dawn blast
"This terrorist operation, a subversive operation of the highest order, took place in a farming area, causing extensive damage," Mr Ghassan al-Adel told Sana.
It did not mention any casualties or if the blast affected oil supply or production.
Two weeks ago, on 13 July, a fire damaged a gas pipeline near the town of Mayadin in the country's main oil and gas-producing region of Deir al-Zour province, activists said at the time.
Oil production in Syria stands at about 350,000 barrels per day, according to official data. It is a key source of income for the Syrian economy, hard hit by more than four months of unrest.
Activists - who are busy preparing for today's demonstrations - have not yet commented on the report.
Protest organisers say that this week's demonstrations are aimed at other Arab countries under the slogan, "Your silence is killing us".
Syrian forces are trying to quell the unrest ahead of Ramadan, which starts this weekend, activists say.
Last night, security forces shot dead three civilians in Deir al-Zour and two in a Damascus suburb, near the town of Zabadani, according to the Syrian Observatory for Human Rights.
It comes a day after at least 10 people were reported to have been killed by government forces in the town of Kanaker, south-west of Damascus.
Last week, President Assad sacked and replaced the governor of Deir al-Zour following anti-government demonstrations in the area that drew hundreds of thousands into the streets.
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